Which of the following is a side effect of Advil?

Ibuprofen, commonly known by the brand name Advil, is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, reduce inflammation, and lower fever. One of the significant side effects associated with the use of Advil is renal problems. This is primarily due to the mechanism by which NSAIDs affect renal blood flow. They inhibit the synthesis of prostaglandins, which play a crucial role in maintaining adequate renal perfusion, especially under conditions of dehydration or other stressors.

Long-term use or high doses of ibuprofen can lead to conditions such as acute kidney injury, chronic kidney disease, or exacerbation of pre-existing renal issues. Therefore, monitoring kidney function is essential for patients using Advil, particularly those with risk factors such as pre-existing renal impairment, elderly patients, or those taking other nephrotoxic drugs.

While gastrointestinal bleeding can indeed occur with NSAIDs due to their effect on the gastric mucosa, the specific mention of renal problems highlights a well-recognized issue directly associated with Advil. Other options such as hypotension and cardiac arrest are not typical direct side effects experienced with ibuprofen use.