Which of the following is a potential side effect of SSRIs?

Prepare for your NCCAOM Biomedicine Board Exam. Study with real-world questions and detailed explanations. Boost your confidence and pass the test!

Weight gain is indeed a potential side effect of selective serotonin reuptake inhibitors (SSRIs). This class of antidepressants is known to cause various changes in metabolism and appetite regulation, which can lead to weight gain in some patients. The exact mechanism is not fully understood, but it is believed that these medications can affect the neurochemical pathways involved in appetite and energy balance.

Several studies have reported that while some patients may experience weight loss when starting SSRIs, others may see an increase in weight over time, especially with long-term use. Factors such as individual differences, duration of treatment, and the specific SSRI being used can all contribute to the varying effects on weight.

In contrast, the other options listed are not typically associated with SSRIs. Dry cough is more commonly related to medications like ACE inhibitors, severe constipation is not a common side effect of SSRIs, and delayed wound healing is more closely tied to other factors, such as the use of corticosteroids, poor nutrition, or chronic conditions affecting healing. Thus, weight gain stands out as a notable side effect of SSRIs among the choices provided.

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