Which blood pressure-related hormone influences fluid balance and is a response to decreased blood volume?

Prepare for your NCCAOM Biomedicine Board Exam. Study with real-world questions and detailed explanations. Boost your confidence and pass the test!

The correct choice in this case is renin. Renin is an enzyme that plays a crucial role in the regulation of blood pressure and fluid balance, particularly in response to decreased blood volume or low blood pressure. When the kidneys detect a drop in blood flow or sodium levels, they secrete renin into the bloodstream.

Renin initiates the renin-angiotensin-aldosterone system (RAAS), starting a cascade of reactions that lead to the production of angiotensin II, which has multifaceted effects, including vasoconstriction and stimulating the secretion of aldosterone. Aldosterone then acts on the kidneys to increase sodium reabsorption, which in turn promotes water retention, ultimately contributing to the increase in blood volume and blood pressure.

While angiotensin II, vasopressin, and aldosterone are all involved in blood pressure regulation and fluid balance, renin is specifically the hormone that responds to decreased blood volume by activating this system, making it foundational to the response mechanism. Understanding how renin and the subsequent hormones interact helps clarify the body’s complex processes of maintaining homeostasis in blood pressure and fluid volume.

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