What is the primary symptom of scurvy?

The primary symptom of scurvy is loose teeth, stemming from the disease's effects on collagen synthesis due to a deficiency in vitamin C (ascorbic acid). Collagen is a crucial protein that helps maintain the integrity of connective tissues, including the gums and periodontal ligament that support the teeth. When there is an inadequate amount of vitamin C, the body cannot effectively produce collagen, leading to weakened gums and the loosening of teeth. Other oral symptoms of scurvy may include gum inflammation and bleeding, which further contribute to the issue of loose teeth.

While edema, severe acne, and joint pain may present in various medical conditions, they are not primary symptoms of scurvy. Edema can occur due to many factors, including nutritional deficiencies, but is not specific to scurvy. Similarly, severe acne is not related to vitamin C deficiency. Joint pain can be a symptom of many ailments, but in the case of scurvy, it is secondary and not the main feature associated with the disease. Thus, loose teeth are the hallmark indicator of scurvy, directly linked to the vitamin C deficiency leading to disrupted collagen formation.